CALEB UPDATE 9/1 - from Colleen and Mike

Our little man is hanging in there.  He has felt very sick this time, having a lot of trouble eating and SUPER low energy. The good news was that they did not find any leukemia cells in his spinal fluid, and it looks as if his Leukemia is genetically almost the same as last time, with very little mutation. As far as long-term treatment plans, that is all still very much in a wait and see phase.  We will not know what the next step of the protocol is until the end of this 28 day re-induction course of chemo.  If he is in remission, and there is no trace of cancer in his blood at that point, that gives us the most options for treatment.  

Best case scenario is a new immunotherapy, blinatumomab, which is a 28 day continuous infusion,  and then another 2.5 year protocol of chemo (similar but more intense to the first time around).  If there is still disease, which they told us happens about 50% of the time, then he would probably move toward something called CAR T-cell Therapy, and then most likely to Bone Marrow Transplant.  So, we are just hoping for full remission. Day 29 will be September 21st and then the results for the test done that day will probably come in a couple days later. 

That is all we know right now. Just trying to take things one day at a time. Thank you all for the incredible love and support.  It means so much to us.